MabVax Therapeutics, Inc. and its collaborators are conducting Phase II clinical trials for the treatment of two cancers; Sarcoma and Ovarian Cancer. Patients are being recruited for each of these trials. Details are available by following the links below.

There are two clinical trials currently underway with vaccines licensed to MabVax.

The first is a vaccine against sarcoma. Find out more…

The second clinical trial is against ovarian cancer. Find out more…

Clinical Trial Participation

What is a clinical trial?

There are many definitions of a clinical trial. They are generally considered to be medical or health-related research studies in humans that follow a pre-defined protocol or study plan. A clinical trial is a research study conducted to answer specific questions about a new treatment or to investigate new ways of using known treatments. Generally, the drug or therapies being investigated in a clinical trial have not been approved by Regulatory agencies (such as the Food and Drug Administration (FDA) in the US). Clinical trials are used to determine whether new treatments or drugs are safe and effective

Why participate in a clinical trial?

Participants in clinical trials gain access to new research treatments before they are widely available and help others by contributing to medical research.

Who can participate in a clinical trial?

There are certain requirements, called inclusion and exclusion criteria which must be met to be eligible to participate in a clinical trial. The inclusion and exclusion criteria are established in advance. These guidelines are an important principle of medical research that helps to produce reliable results. Inclusion and exclusion criteria are often related to:

• Age
• Gender
• Type and stage of a disease
• Previous treatment history
• Previous and current medications
• Recent medical conditions
• Before joining a clinical trial, a participant must qualify for the study by meeting the inclusion/exclusion criteria.

Be sure to discuss your interest in participating in a clinical trial with your doctor who may refer you to a specific clinical trial.

What are the benefits and risks of participating in a clinical trial?

Benefits

Clinical trials that are well-designed and well-executed are the best approach for eligible participants to:

• Play an active role in their own health care.
• Access investigational treatments before they are widely available.
• Obtain expert medical care at leading health care facilities during the trial.
• Help others with the same condition by contributing to medical research.
• Play a role in the discovery of treatments, cures and prevention for certain diseases or medical conditions.

Risks

There are risks to clinical trials.

• There may be unpleasant, serious or even life-threatening side effects to experimental treatment.
• The experimental treatment may not be effective for the participant.
• The study protocol may require more time and attention than would a non-protocol treatment, including trips to the study site, more treatments, hospital stays or complex dosage requirements.